Mass Spectrometry Scientist (LC-MS/MS – Peptides/Proteomics)

Job Description

We are seeking a Mass Spectrometry Scientist (LC-MS/MS – Peptides/Proteomics) to support advanced peptide characterization and modification analysis using high-resolution mass spectrometry. This role is highly technical and focused on method development, workflow optimization, and complex data interpretation to support molecular characterization efforts.

The ideal candidate will bring strong experience with peptide mapping and MS/MS fragmentation techniques in a laboratory environment.

Key Responsibilities

• Develop, optimize, and execute accurate-mass LC-MS/MS workflows for peptide identification, sequence confirmation, and modification analysis
• Apply high-resolution MS and MS/MS fragmentation techniques (CID, HCD, ETD) for confident identification and site localization of peptide modifications and isomers
• Optimize sample preparation and enzymatic digestion workflows to enhance detection of low-abundance species
• Analyze and interpret complex proteomic and peptide datasets using industry-standard software
• Advance and refine LC-MS/MS methods to support broader structural and molecular characterization initiatives
• Document experimental procedures, results, and interpretations following best practices
• Communicate findings clearly to cross-functional scientific teams

Qualifications

Required

• Hands-on experience with LC-MS/MS for peptide/proteomic analysis, including fragmentation techniques (CID, HCD, ETD)
• Strong problem-solving skills with ability to work independently and collaboratively
• Degree in Chemistry, Biochemistry, or related field:
  • BS: 5–8 years
  • MS: 3–6 years
  • PhD: 0–2 years
    (or equivalent experience)
• Authorization to work in the U.S. without sponsorship

Preferred

• Experience with LC-MS/MS method development and optimization
• Familiarity with proteomics/data analysis software (e.g., Mascot, Proteome Discoverer, Byonic, etc.)
• Experience in a GMP or regulated environment
• Knowledge of LIMS or data management systems

Additional Information

The position is Full Time, Monday through Friday, 8am-5pm, with overtime as needed. Candidates living within a commutable distance of Andover, MA, are encouraged to apply.

What we offer:

• Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays
• Yearly goal-based bonus & eligibility for merit-based increases
• Hourly rate is between $30.00-$33.00, depending on education and experience

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.