Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit grail.com

This is a US field-based position responsible for communicating and refining health economic and outcomes research (HEOR) evidence that supports payer engagement activities across GRAIL’s diagnostic portfolio. This is accomplished through high-quality, non-promotional scientific exchange, including payer-focused education, evidence discussions, and responses to unsolicited medical and scientific inquiries.

In this position, you will partner closely with the Market Access Payer Engagement and Government Affairs teams, serving as a scientific and economic subject matter expert (SME) when payer-facing interactions require deep HEOR expertise. The role combines scientific and clinical fluency with strong understanding of payer evidence expectations, reimbursement considerations, and value communication. This role partners closely with Medical Affairs, Market Access, Government Affairs, and Commercial teams and plays a critical role in shaping payer value narratives and supporting evidence-based messaging.

### Responsibilities:

Support scientific exchange related to payer-facing evidence resources, including AMCP dossiers, evidence summaries, and value communication materials

Partner with Market Access teams to translate complex clinical, economic, and real-world evidence into clear, payer-relevant insights

Act as the HEOR subject matter expert in payer engagements, particularly for deep-dive evidence discussions, and elicit, capture, and communicate relevant payer insights

Communicate clinical, health economic, outcomes, and real-world evidence relevant to payer coverage and reimbursement decisions

Demonstrate strong working knowledge of payer evidence frameworks, budget impact concepts, value narratives, and real-world evidence methodologies

Summarize and communicate complex medical, scientific, and economic concepts clearly to both external stakeholders and internal partners

As part of the HEOR team, identify data gaps and inform future research priorities to address payer needs

Support development and refinement of value frameworks and evidence summaries to enhance payer value demonstration, including those focused on economic modeling

Ensure consistency and scientific rigor across all payer-facing economic content and messaging

Ensure all activities and interactions adhere to corporate compliance policies and healthcare regulations

Participate in regional and national meetings in support of medical and access objectives

Support internal education on payer value and health economics communication

Maintain clinical, scientific, and health economic expertise relevant to GRAIL’s products

Engage in continuous learning to stay current on diagnostics, payer policy trends, guidelines, and evolving evidence requirements

### Required Qualifications:

Advanced degree in a relevant discipline (PhD, PharmD, MD, MPH, MS, or equivalent) with training in health economics, outcomes research, epidemiology, or related field

Minimum 3 years of experience in HEOR, Market Access, or Medical Affairs within diagnostics, biotechnology, or pharmaceuticals

Deep experience and expertise in payer landscape which could include developing payer value materials, working within a payer, or engaging payers

Strong analytical, problem-solving, and communication skills

Familiarity with health economic modeling methodologies and real-world evidence analysis

Ability to engage confidently with senior payer stakeholders and subject-matter experts

Understanding of US payer evidence requirements and coverage decision drivers

Ability to work independently while maintaining strong cross-functional collaboration

Willingness to travel extensively (approximately 25 - 35%) in support of internal collaboration and external engagements

The expected, full-time, annual base pay scale for this position is $235K - $312K. Actual base pay will consider skills, experience, and location.

This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.

GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [email protected] if you require an accommodation to apply for an open position.

GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!

Managed Care Liaison (MCL) / Health Economics Field Lead # 4545

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GRAIL