Research Specialist / Sr Scientist, Assay Sciences, Discovery Pharmacology

What You Will Contribute To Altos

At Altos, your work will be at the heart of a mission to transform medicine by reversing disease and restoring cell health. You will contribute to the development of a new generation of drugs rooted in an advanced understanding of cellular rejuvenation and resilience.

As a Research Specialist or Sr Scientist of Assay Sciences, Discovery Pharmacology team, your primary focus will be supporting the needs of development and operation of a wide range of analytical and bioassays within the Drug Discovery and Development (3DS) division of Altos. This is a laboratory research scientist position focused on the development and execution of cell-based and biochemical assays, and complex in vitro bioassays. Your work will contribute to our drug discovery campaigns across a diverse portfolio of discovery and development stage projects. Your expertise will be instrumental in driving our mission and making a significant impact in aging/rejuvenation biology and drug discovery.

Responsibilities

• You'll be right in the middle of drug discovery, developing the next generation of medicines.
• Your main gig is making, running, and optimizing a ton of analytical and bioassays (cell-based, biochemical, complex in vitro).
• You'll be taking manual assays and turning them into super-efficient, automated processes—think moving from a bench to high-throughput screening with automated gear.
• You'll need to nail the stats (Z’-factor!) and make sure everything is scalable.
• Creating new assays from scratch (de novo development) is also on the list.
• Documenting everything in the electronic lab notebook (ELN) for awesome data integrity.
• Working with other teams, including the Discovery Sciences, Institute of Computation and Product Development crew.
• You'll be a technical lead for the assay sciences team.
• You'll also be managing external research partners (CROs) to make sure their data is top-notch.

Who You Are

Required Qualifications

• Research Specialist Experience Requirement: Bachelors or Masters degree and 8+ years of industry experience.
• Sr Scientist Experience Requirements: PhD and 6+ years post-PhD, PLUS 3+ years of industry experience.
• Seriously good at developing and running a huge variety of analytical and bioassays.
• You should know your way around cutting-edge assay tech like MSD, HTRF, AlphaLISA, etc.
• Expertise with lab automation gear is a must (Bravo, Echo, I.DOT, Digital Dispenser, etc.).
• Experience with high-content imaging in high-throughput (96- and 384-well) formats.
• You need to be a productive rockstar who can get work done on time.
• Great at documenting your experiments in an ELN.
• Proven experience managing external CROs.
• Excellent communication and organizational skills—ready to multitask
• An SME / emerging leader in a technical field with sustained performance and accomplishment.
• Strong demonstrable expert knowledge of a specialized research area with a wide breadth of knowledge beyond a research specialty.
• Demonstrates ability to apply excellent professional judgement and high proficiency of application of all skills and techniques relevant to lab / hub research projects.

The salary range for Redwood City:

• Research Specialist: $129,500 - $166,000
• Senior Scientist I, In Vitro Pharmacology $176,000 - $225,700

Exact compensation may vary based on skills, experience, and location.

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