Controller
Posted 18 days ago
Position Overview
We are seeking a highly strategic and operationally sophisticated Controller to architect and lead the next phase of the company’s financial infrastructure and accounting operations. This individual will serve as a key finance leader during a period of rapid growth, helping establish the rigor, scalability, and operational discipline required for a world-class organization.
The ideal candidate is both visionary and execution-oriented: someone who embraces modern finance technologies, including AI-enabled workflows and automation, while maintaining uncompromising standards around accuracy, controls, and financial stewardship. This role requires a builder’s mindset, strong business judgment, and the ability to operate effectively in an evolving, high-growth environment.
This leader will partner closely with executive leadership, external advisors, auditors, investors, and cross-functional teams to strengthen financial operations, improve organizational visibility, and help position the company for long-term strategic expansion.
Key Responsibilities
Strategic Accounting & Financial Leadership
Lead all core accounting operations, including general ledger, accounts payable, accounts receivable, payroll, treasury, and monthly close activities
Oversee the preparation of timely, accurate, and decision-useful monthly, quarterly, and annual financial reporting
Establish scalable accounting policies, governance frameworks, and internal control environments appropriate for a rapidly evolving organization
Ensure compliance with GAAP and other applicable financial and regulatory standards
Partner with external audit firms, tax advisors, banking institutions, and financial service providers to support the company’s evolving operational needs
Drive continuous enhancement of financial reporting quality, operational transparency, and organizational accountability
Oversee cash management, liquidity planning, and banking relationships
Operational Scale & Systems Transformation
Build and modernize financial infrastructure capable of supporting substantial organizational growth and increasing operational complexity
Champion process automation and intelligent workflow design, leveraging emerging technologies and AI-enabled tools where appropriate to improve efficiency, scalability, and insight generation
Evaluate, implement, and optimize financial systems, ERP platforms, and reporting technologies to strengthen operational performance
Develop executive and board-level reporting frameworks, dashboards, and KPI visibility tools that support strategic decision-making
Strengthen enterprise-wide financial processes to support future readiness, operational resilience, and scalable governance
Cross-Functional & External Partnership
Partner closely with executive leadership on forecasting, budgeting, strategic planning, and organizational prioritization
Collaborate across Finance, Operations, HR, Legal, and scientific leadership to align financial processes with business objectives
Support financing activities, investor diligence processes, and strategic transactions as needed
Serve as a trusted advisor to functional leaders by providing actionable financial insights and operational guidance
Build strong relationships with external stakeholders, including auditors, consultants, legal counsel, and institutional partners
Team Development & Organizational Leadership
Recruit, mentor, and develop a high-performing accounting and finance organization
Foster a culture grounded in operational excellence, accountability, innovation, and continuous improvement
Develop scalable organizational structures, workflows, and operating rhythms that evolve alongside company growth
Elevate the finance function into a proactive strategic partner across the business
Qualifications
Required
10+ years of progressive accounting and finance leadership experience, including substantial experience within high-growth or rapidly scaling organizations
Bachelor’s degree in Accounting, Finance, or related discipline; CPA
Demonstrated success building and evolving financial infrastructure in dynamic, fast-paced environments
Deep understanding of GAAP, financial reporting, internal controls, and accounting operations
Experience leading audits, managing external accounting relationships, and navigating increasingly sophisticated operational requirements
Strong systems orientation with experience implementing scalable processes and financial technologies
Exceptional analytical, organizational, and communication skills
Proven ability to influence cross-functional stakeholders and operate effectively in ambiguous, rapidly evolving environments
Preferred
Experience with NetSuite or other enterprise ERP platforms
Familiarity with AI-enabled finance tools, workflow automation technologies, and modern financial systems architecture
Experience supporting venture-backed, growth-stage, or technology-driven organizations
Background within biotechnology, healthcare, diagnostics, life sciences, or adjacent innovation-focused industries preferred
What Success Looks Like
Financial operations scale seamlessly alongside organizational growth
Reporting, controls, and operational processes provide leadership with high-confidence visibility and actionable insight
The finance organization becomes increasingly predictive, technology-enabled, and strategically integrated across the business
Systems, governance frameworks, and operational rigor mature proactively ahead of company complexity
Leadership, investors, and external stakeholders develop strong confidence in the integrity and scalability of the company’s financial infrastructure
Location: Onsite, San Diego, CA
Employment Type: Full-Time
Compensation: The starting salary range for this position ($190,000.00 - $230,000.00) encompasses multiple job levels. Final compensation, including title and level, will be determined based on a candidate's qualifications, experience, and demonstrated skills throughout the hiring process.
We are an equal opportunity employer. We thrive on diversity and collaboration.
Foresite Labs creates companies at the intersection of AI/machine learning and science. We believe AI, generative AI, and data science—when applied with scientific rigor—can accelerate discovery and drive innovations that benefit humanity. We provide the foundation for bold ideas to take shape and accelerate, shaping a better future for all. We offer competitive salaries, excellent benefits, and a flexible work environment where employees learn from top thinkers across multiple disciplines. With headquarters in San Francisco and Boston, we’re building a culture where scientific rigor meets entrepreneurial ambition. Foresite Labs Values Truth over progression: We follow the science, pursuing ideas that are grounded in data and abandoning them when not supported by the evidence. Take good risks: Our culture values informed risk-taking: good decisions are celebrated even when they result in bad outcomes. Everyone feels safe to contribute ideas and to learn from failure. Single accountable person: The project team lead is accountable for all decisions and for maintaining transparency and information flow within the team; we trust the project teams. The Review Committee unlocks capital and sets directions. Simplicity and Focus: “Companies die from indigestion, not starvation” (Bill Hewlett) We will focus on a few ideas aggressively and minimize all other distractions. Everyone will have a few key goals that have measurable outcomes. Respect and Community: Our employees are our greatest asset; everyone invests in creating an environment of collaboration and respect. We support their careers and career development whether they stay, go to a Labs company, or end up somewhere else.
Key team members

Alex Aravanis MD PhD

Damien Soghoian

Christopher Baldwin

Kylie Reynolds
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