Director, Product Management - BioPharma

Company Description

Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.

Job Description

About the Product Department

Our Oncology Product team is responsible for the strategy and lifecycle management of our oncology portfolio, and is comprised of two core areas:

• Assay Products: Liquid and tissue-based diagnostics for therapy selection and disease monitoring
• Digital Products: External-facing digital/data solutions and internal infrastructure supporting clinical and commercial operations

About The Role

The Director, Biopharma Diagnostics-Product Management is a leadership position reporting to our Senior Director of Product Management. You would lead the strategy, development, and commercialization of Guardant’s biopharma-focused diagnostics portfolio, ensuring our products are clinically impactful, scientifically rigorous, and aligned with the needs of our biopharma partners.  Viable candidates will have deep expertise in oncology diagnostics, and a passion for driving innovation at the intersection of medicine, product strategy, and biopharma collaboration.  While not a requirement, this is an ideal opportunity for clinically-trained MDs, PhDs, or MD/PhDs to work at the forefront of oncology diagnostics. 

Key Responsibilities

Strategic Leadership & Portfolio Management

• Define and execute a comprehensive product strategy aligned with Guardant’s biopharma business objectives and oncology roadmap
• Lead cross-functional teams to design, develop, and deliver best-in-class assay and digital products for therapy selection and disease monitoring
• Translate market insights and partner needs into actionable product plans, identifying unmet needs and prioritizing opportunities

Biopharma Engagement & Innovation

• Serve as the primary product liaison to the biopharma business unit, ensuring alignment with biomarker-driven trials, companion diagnostics, and regulatory strategies
• Drive co-development partnerships and data generation initiatives to support product innovation and reimbursement
• Monitor emerging trends, technologies, and competitive activity to inform product differentiation and future roadmap

Clinical Integration & Commercialization

• Ensure products integrate seamlessly into oncology workflows—physician, nurse, and patient—to maximize adoption and usability
• Collaborate with Medical Affairs and Market Access to develop evidence strategies that demonstrate clinical utility and support payer engagement
• Oversee launch planning, sales enablement, and field training to ensure commercial readiness

Cross-Functional Collaboration

• Partner with R&D, Clinical Development, Regulatory, and Commercial teams to drive execution across the product lifecycle
• Represent Guardant externally with oncologists, healthcare systems, payers, and biopharma stakeholders to refine value propositions and identify unmet needs
• Contribute to publication planning, clinical conference presentations, and scientific communications

Qualifications

Required

• A Bachelor’s degree and 15 years of related experience or 10-12 years with a Master’s degree; 8 years with a PhD; or 5 years with a PharmD/MD
• 8+ years of experience in product management, medical affairs, or biopharma strategy within oncology diagnostics or precision medicine
• Proven success in launching and scaling diagnostic or healthcare products
• Strong understanding of liquid biopsy, molecular diagnostics, and biomarker-driven oncology

Preferred

• Master’s and/or advanced scientific degree is highly preferred
• Experience in companion diagnostics, biomarker development, or clinical trial integration
• Familiarity with payer dynamics, evidence generation, and reimbursement strategies
• Exceptional communication, analytical, and leadership skills with the ability to influence across scientific, clinical, and commercial domains

Additional Information

Hybrid Work Model: At Guardant Health, we have defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

The US base salary range for this full-time position is $155,300 to $213,560. The range does not include benefits, and if applicable, bonus, commission, or equity. The range displayed reflects the minimum and maximum target for new hire salaries across all US locations for the posted role with the exception of any locations specifically referenced below (if any).

For positions based in Palo Alto, CA or Redwood City, CA, the base salary range for this full-time position is $182,700 to $251,250. The range does not include benefits, and if applicable, bonus, commission, or equity.

Within the range, individual pay is determined by work location and additional factors, including, but not limited to, job-related skills, experience, and relevant education or training. If you are selected to move forward, the recruiting team will provide details specific to the factors above.

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com

A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

• All your information will be kept confidential according to EEO guidelines.
• To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.

Please visit our career page at: http://www.guardanthealth.com/jobs/