Director, Health Systems
Karius.com
Office
Eastern Region
Full Time
About KariusKarius is a venture-backed life science startup that is transforming the way pathogens and other microbes are observed throughout the body. By unlocking the information present in microbial cell-free DNA, we're helping doctors quickly solve their most challenging cases, providing industry partners with access to 1000’s of biomarkers to accelerate clinical trials, discovering new microbes, and reducing patient suffering worldwide.
Position SummaryThe Director, Health Systems is a pivotal leadership role responsible for developing and executing strategies to expand the adoption of the Karius Test across Health Systems and IDNs. This individual will build and manage executive-level relationships, establish Centers of Excellence, and cultivate Clinical Champions to drive enterprise-wide adoption. The Director will serve as the primary point of coordination across Sales, Medical, Legal, Marketing, and Customer Success teams, ensuring alignment and accountability in health system engagements. By combining strategic insight, operational excellence, and customer advocacy, this role will enable Karius to strengthen its position as a trusted partner to leading healthcare organizations and accelerate growth through long-term, system-wide partnerships.
Why Should You Join Us?Karius aims to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company’s platform is already delivering unprecedented insights into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood, and helping industry accelerate the development of therapeutic solutions. The Karius test we provide today is one of the most advanced solutions available to physicians who aim to deliver better care to many otherwise ineffectively treated patients. Our test is the result of some incredible work done by our scientists, statisticians, engineers, and physicians, all driven by the same mission. You, as part of the Karius team, will be able to see how directly your work has a life-changing impact on people, and at scale. Reports to: VP of Commercial Strategy and Health Systems
Location: East Coast Region, Remote
Primary Responsibilities• Develop and execute strategies to expand Karius adoption across Health Systems and IDNs, including academic medical centers and large regional networks.• Build trusted, long-term relationships with executive leaders, administrators, and clinical stakeholders to ensure enterprise-level integration of the Karius Test.• Secure and manage enterprise agreements, contracts, and renewals in collaboration with Legal, ensuring alignment with company goals and compliance requirements.• Lead Business and Utilization Reviews with system executives, demonstrating clinical, operational, and financial return on investment.• Identify and prioritize new opportunities for expansion within health systems, including additional sites, service lines, and affiliated networks.• Foster and maintain strategic relationships with key external partners, including industry consortia, diagnostic alliances, and integrated health networks, to enhance Karius’s market presence and collaborative growth opportunities.• Serve as a trusted liaison between Karius and strategic partners to ensure alignment on shared goals, joint initiatives, and long-term partnership success.• Collaborate with Sales, Medical Affairs, Marketing, Legal, and Customer Success to ensure coordinated execution, test volume growth, new account generation, and consistent system-level messaging.• Partner with field leaders to align execution with strategic account priorities. Establish Centers of • Excellence and cultivate Clinical Champions to accelerate adoption and advocacy across health systems.• Provide insights from health system engagements to refine commercial strategy, product positioning, and evidence generation.• Represent Karius at executive-level meetings, national conferences, and health system forums to strengthen visibility and credibility.• Promote partnership successes and expand advocacy across Health Systems and IDNs to drive broader adoption.• Monitor healthcare trends, policy developments, and competitor activities to inform strategy and maintain market leadership.• Ensure account activities and strategies are documented in Salesforce and tracked against commercial KPIs.• Support forecasting, pipeline reviews, and account planning with actionable, system-level insights.Maintain accountability for execution while ensuring scalability and sustainability of health system strategies.
What’s Fun About the Job?Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters.
Travel: Travel up to 50%
Physical RequirementsSubject to extended periods of sitting and/or standing, vision to monitor and moderate noise levels. Work is generally performed in an office, lab or clinical environment.
Position Requirements• Bachelor’s degree in Business, Healthcare Administration, or a related field.• Advanced degree (MBA, MPH, or equivalent) preferred.• 8+ years of experience in healthcare partnerships, sales, or business development, with a strong focus on strategic accounts and regional account management.• Proven success in negotiating and managing high-value partnerships in the healthcare or biotech industry.• Strong relationship-building and consultative selling skills.• Exceptional communication, negotiation, and presentation abilities.• Proven ability to manage complex sales cycles and multi-stakeholder engagements.• Proficiency in CRM tools (e.g., Salesforce) and data-driven decision-making• Experience with co-promotion strategies and partnership enablement.• Extensive knowledge of the biotech or medical diagnostics industry.• Familiarity with hospital operations and decision-making processes.
Personal Qualifications• Demonstrates a forward-thinking approach with the ability to craft and implement strategic initiatives that align with both immediate and long-term business objectives.• Excels at building trust and credibility with key stakeholders, including executive-level decision-makers, physicians, and department leaders.• Exceptional ability to communicate complex ideas clearly and persuasively, tailoring messages to diverse audiences, from healthcare professionals to internal teams.• Strong aptitude for analyzing data, market trends, and customer feedback to inform strategic decisions and refine partnership approaches.• Thrives in a fast-paced, dynamic environment with the ability to pivot strategies based on evolving market conditions and organizational priorities.• Demonstrates resourcefulness and a solution-oriented mindset, effectively overcoming challenges to drive results.• Deep commitment to understanding customer needs and delivering value through innovative solutions and exceptional service.• Operates with a high degree of professionalism, ethical standards, and accountability for delivering on commitments. DisclaimerThe above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of Karius.
Equal Opportunity EmployerAt Karius, we value a diverse and inclusive workplace and provide equal employment opportunities for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company. All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual’s race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at recruiting@kariusdx.com and we will accommodate qualified individuals with disabilities.
Position SummaryThe Director, Health Systems is a pivotal leadership role responsible for developing and executing strategies to expand the adoption of the Karius Test across Health Systems and IDNs. This individual will build and manage executive-level relationships, establish Centers of Excellence, and cultivate Clinical Champions to drive enterprise-wide adoption. The Director will serve as the primary point of coordination across Sales, Medical, Legal, Marketing, and Customer Success teams, ensuring alignment and accountability in health system engagements. By combining strategic insight, operational excellence, and customer advocacy, this role will enable Karius to strengthen its position as a trusted partner to leading healthcare organizations and accelerate growth through long-term, system-wide partnerships.
Why Should You Join Us?Karius aims to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company’s platform is already delivering unprecedented insights into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood, and helping industry accelerate the development of therapeutic solutions. The Karius test we provide today is one of the most advanced solutions available to physicians who aim to deliver better care to many otherwise ineffectively treated patients. Our test is the result of some incredible work done by our scientists, statisticians, engineers, and physicians, all driven by the same mission. You, as part of the Karius team, will be able to see how directly your work has a life-changing impact on people, and at scale. Reports to: VP of Commercial Strategy and Health Systems
Location: East Coast Region, Remote
Primary Responsibilities• Develop and execute strategies to expand Karius adoption across Health Systems and IDNs, including academic medical centers and large regional networks.• Build trusted, long-term relationships with executive leaders, administrators, and clinical stakeholders to ensure enterprise-level integration of the Karius Test.• Secure and manage enterprise agreements, contracts, and renewals in collaboration with Legal, ensuring alignment with company goals and compliance requirements.• Lead Business and Utilization Reviews with system executives, demonstrating clinical, operational, and financial return on investment.• Identify and prioritize new opportunities for expansion within health systems, including additional sites, service lines, and affiliated networks.• Foster and maintain strategic relationships with key external partners, including industry consortia, diagnostic alliances, and integrated health networks, to enhance Karius’s market presence and collaborative growth opportunities.• Serve as a trusted liaison between Karius and strategic partners to ensure alignment on shared goals, joint initiatives, and long-term partnership success.• Collaborate with Sales, Medical Affairs, Marketing, Legal, and Customer Success to ensure coordinated execution, test volume growth, new account generation, and consistent system-level messaging.• Partner with field leaders to align execution with strategic account priorities. Establish Centers of • Excellence and cultivate Clinical Champions to accelerate adoption and advocacy across health systems.• Provide insights from health system engagements to refine commercial strategy, product positioning, and evidence generation.• Represent Karius at executive-level meetings, national conferences, and health system forums to strengthen visibility and credibility.• Promote partnership successes and expand advocacy across Health Systems and IDNs to drive broader adoption.• Monitor healthcare trends, policy developments, and competitor activities to inform strategy and maintain market leadership.• Ensure account activities and strategies are documented in Salesforce and tracked against commercial KPIs.• Support forecasting, pipeline reviews, and account planning with actionable, system-level insights.Maintain accountability for execution while ensuring scalability and sustainability of health system strategies.
What’s Fun About the Job?Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters.
Travel: Travel up to 50%
Physical RequirementsSubject to extended periods of sitting and/or standing, vision to monitor and moderate noise levels. Work is generally performed in an office, lab or clinical environment.
Position Requirements• Bachelor’s degree in Business, Healthcare Administration, or a related field.• Advanced degree (MBA, MPH, or equivalent) preferred.• 8+ years of experience in healthcare partnerships, sales, or business development, with a strong focus on strategic accounts and regional account management.• Proven success in negotiating and managing high-value partnerships in the healthcare or biotech industry.• Strong relationship-building and consultative selling skills.• Exceptional communication, negotiation, and presentation abilities.• Proven ability to manage complex sales cycles and multi-stakeholder engagements.• Proficiency in CRM tools (e.g., Salesforce) and data-driven decision-making• Experience with co-promotion strategies and partnership enablement.• Extensive knowledge of the biotech or medical diagnostics industry.• Familiarity with hospital operations and decision-making processes.
Personal Qualifications• Demonstrates a forward-thinking approach with the ability to craft and implement strategic initiatives that align with both immediate and long-term business objectives.• Excels at building trust and credibility with key stakeholders, including executive-level decision-makers, physicians, and department leaders.• Exceptional ability to communicate complex ideas clearly and persuasively, tailoring messages to diverse audiences, from healthcare professionals to internal teams.• Strong aptitude for analyzing data, market trends, and customer feedback to inform strategic decisions and refine partnership approaches.• Thrives in a fast-paced, dynamic environment with the ability to pivot strategies based on evolving market conditions and organizational priorities.• Demonstrates resourcefulness and a solution-oriented mindset, effectively overcoming challenges to drive results.• Deep commitment to understanding customer needs and delivering value through innovative solutions and exceptional service.• Operates with a high degree of professionalism, ethical standards, and accountability for delivering on commitments. DisclaimerThe above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of Karius.
Equal Opportunity EmployerAt Karius, we value a diverse and inclusive workplace and provide equal employment opportunities for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company. All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual’s race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at recruiting@kariusdx.com and we will accommodate qualified individuals with disabilities.
Director, Health Systems
Office
Eastern Region
Full Time
October 8, 2025