Research Service Professional (iPSC Editing Specialist)

• University of Colorado Anschutz Medical Campus
• Department: Pharmacology / Functional Genomics Facility
• Job Title: Research Service Professional (iPSC Editing Specialist)
• Position #00839642 – Requisition # 37909

Job Summary:

We are urgently seeking a dynamic Research Scientist to lead a high-priority project focused on precision editing of induced pluripotent stem cells (iPSCs). This role is central to advancing our capabilities in disease modeling and therapeutic discovery in the field of Down Syndrome. The ideal candidate will have deep expertise in genome editing (e.g., CRISPR), stem cell biology, and functional genomics, and will drive innovation in editing strategies and platform development.

This is a pivotal opportunity to shape a transformative research initiative with broad translational impact. Join us in pushing the boundaries of stem cell engineering.

Key Responsibilities / Duties: (There should be 10+ duties, and duties should be grouped under a section header collectively; the section headers add up to 100%)

iPSC editing and analysis

• Ipsc Culture

• CRISPR-mediated gene editing in iPSC lines
• Perform RNA, DNA, and protein extraction and quality control, as well as other various molecular biology-related assays (qPCR, dPCR, western blot, amplicon sequencing, NGS library preparation, etc.)

Inventory, storage and management of biospecimens; associated record keeping

• Manage edited iPSC inventory in collaboration with the Human Trisome Project biobank, Crnic Institute clinical trials, and associated investigations
• Edited iPSC record keeping

Collaborate with researchers from other programs within the Crnic Institute (clinical, experimental models, data teams) to accomplish project goals and share research results

• Assist senior staff in the design, execution and evaluation of research investigations, including literature reviews, performing experiments and pilots, data integration, and analysis

Foundational lab maintenance responsibilities

• Assist with various laboratory and clinical support operations, such as autoclaving, inventories, ordering supplies, and hazardous materials management.
• Prepare lab for daily operations, including stocking materials, equipment, safety, cleanliness, and related areas

Work Location:

Onsite – this role is expected to work onsite and is located in Aurora, CO.

Why Join Us:

Join a mission-driven team at the forefront of precision medicine and genetic research. The Functional Genomics Shared Resource (FGSR), a leading core facility specializing in gene function analysis, has partnered with the Linda Crnic Institute for Down Syndrome—the largest academic hub for Down syndrome research globally. Together, we are advancing transformative science that directly improves health outcomes for individuals with Down syndrome.

As part of our iPSC team, you’ll contribute to cutting-edge work in gene editing and functional validation of iPSC lines, helping build a gene-corrected iPSC panel that will serve as a foundational resource for future discoveries. You’ll gain hands-on experience with CRISPR-based heterozygous gene editing technology, and a wide array of functional assays—all while working in a collaborative, intellectually stimulating environment.

We’re looking for detail-oriented, motivated, and enthusiastic Laboratory Science Professionals who are passionate about making a real-world impact through science. If you thrive in fast-paced research setting and want to be part of a team that values innovation, precision, and purpose—this is your opportunity to make a difference.

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options
• Dental: Multiple plan options
• Additional Insurance: Disability, Life, Vision
• Retirement 401(a) Plan: Employer contributes 10% of your gross pay
• Paid Time Off: Accruals over the year
• Vacation Days: 22/year (maximum accrual 352 hours)
• Sick Days: 15/year (unlimited maximum accrual)
• Holiday Days: 10/year
• Tuition Benefit: Employees have access to this benefit on all CU campuses
• ECO Pass: Reduced rate RTD Bus and light rail service
• There are many additional perks & programs with the CU Advantage.
• Medical: Multiple plan options
• Dental: Multiple plan options
• Additional Insurance: Disability, Life, Vision
• Retirement 401(a) Plan: Employer contributes 10% of your gross pay
• Paid Time Off: Accruals over the year
• Vacation Days: 22/year (maximum accrual 352 hours)
• Sick Days: 15/year (unlimited maximum accrual)
• Holiday Days: 10/year
• Tuition Benefit: Employees have access to this benefit on all CU campuses
• ECO Pass: Reduced rate RTD Bus and light rail service
• There are many additional perks & programs with the CU Advantage.

Qualifications:

Minimum Qualifications:

• A bachelor’s degree in biology, molecular biology, chemistry, genetics, or a directly related field from an accredited institution
• One (1) year of professional-level experience

Preferred Qualifications:

• A master’s degree in biology, molecular biology, chemistry, genetics, or a directly related field from an accredited institution
• Two (2) years of professional-level experience
• Individuals with advanced degree and research experience are encouraged to apply
• Experience with iPSC maintenance, differentiation, and experimentation
• Experience in CRISPR technology
• Experience independently researching, synthesizing, and presenting novel and assigned topics.
• Experience in training all ability levels (e.g., interns, colleagues) in sample processing procedures.  

Competencies: Knowledge, Skills, and Abilities

• Ability to communicate effectively, both in writing and orally.
• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.
• Ability to work with iPSC using established protocols.
• Flexibility and adaptability to schedule changes, including occasional night and weekend hours.
• Knowledge of aseptic technique and standard cell culture practices
• Must be hard-working, independent yet team-oriented, flexible, and able to communicate effectively.
• Self-motivated and highly organized, with demonstrated project planning and management skills in an academic research setting.
• Strong qualitative analysis skills
• Strong word processing skills, particularly with advanced Excel functions
• Ability to manage the lab
• Demonstrated ability to plan, present, and conduct independent experiments. 
• Willingness and working knowledge to assist the clinical research team and animal research team as needed. 
• Familiarity with genomic, gene expression, proteomic, and metabolomic platforms.

How To Apply:

For full consideration, please submit the following document(s):

1. 1.   A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position
2. 2.   Curriculum vitae / Resume
3. 3.   Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address

Questions should be directed to: Molishree Joshi, Molishree.joshi@cuanschutz.edu

Screening Of Applications Begins:

Immediately and continues until position is filled.

Anticipated Pay Range:

Equal Employment Opportunity Statement:

The starting salary range (or hiring range) for this position has been established as HIRING RANGE ($50,357 - $64,054).

The above salary range (or hiring range) represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

CU is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.

Ada Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu​.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program.