Senior Director, Field Medical Affairs

Amylyx is a clinical-stage pharmaceutical company based in Cambridge, Massachusetts, with an audacious mission to develop novel therapies for high unmet needs. We are currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, progressive supranuclear palsy (PSP), and amyotrophic lateral sclerosis (ALS). Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve.

Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – create a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and determination, we encourage you to read the opportunity below and apply.

The Opportunity

Amylyx is seeking a Senior Director, US Field Medical, who will recruit, train, and manage a team of Field Medical professionals (MSLs) to execute the company's medical strategy with an initial  focus on the lead program, Avexitide in post-bariatric hypoglycemia (PBH), while also overseeing field medical strategy across Amylyx’s broader and expanding therapeutic portfolio. This leadership role involves driving the vision for field-based activities, overseeing medical and scientific engagement with key opinion leaders (KOLs), and leveraging insights to inform business and clinical strategy. The Senior Director acts as a critical link between the field team and cross-functional leadership, including Medical Affairs, Commercial, Clinical Development, and Research and Development (R&D).

Responsibilities

Strategic Leadership:

• Develop and execute the national field medical strategy in alignment with the broader Medical Affairs and company objectives. Define the vision, set strategic goals, design and report KPIs, and ensure tactical execution across the field team.

Team Management And Development:

• Recruit, hire, train, and manage a high-performing field medical team. Foster a culture of scientific excellence, accountability, and continuous learning. Provide mentorship, coaching, and career development opportunities to team members.

Medical And Scientific Engagement:

• Oversee the team's scientific exchange activities with external stakeholders, including national and regional KOLs, healthcare providers (HCPs), and professional medical societies. Ensure the team delivers timely, impactful data and communicates scientific information accurately and compliantly.

Cross-Functional Collaboration And Leadership:

• Partner closely with internal departments—including Medical Affairs, Commercial, Clinical Development, R&D, Market Access, and Regulatory—to ensure alignment and support for product launches, payer engagements, clinical trial activities, and other strategic initiatives.

Insight Generation:

• Establish a process for gathering, summarizing, and disseminating field-based medical insights to internal stakeholders to inform strategic decision-making and identify educational gaps.

Compliance And Operations:

• Ensure all field medical activities adhere to company Standard Operating Procedures (SOPs) and regulatory and compliance guidelines. Oversee operational aspects, including budget management, performance tracking, and the effective use of customer relationship management (CRM) systems.

Required Qualifications

• An advanced degree is required, such as a PharmD, MD, PhD, or equivalent.
• A minimum of 10 years of relevant experience in the pharmaceutical or biotech industry, with at least 5 years in a field medical leadership role with people management responsibilities.
• Strong understanding of drug development, clinical trial methodology, and industry regulations and guidelines governing field medical activities, including the PhRMA code and FDA promotional guidelines. Experience/expertise in endocrinology/obesity medicine strongly preferred.
• Proven track record of leading and developing high-performing teams. Must possess strong strategic, organizational, communication, and interpersonal skills.
• Requires significant travel, often up to 60% domestically, to attend scientific conferences, internal meetings, and field visits.

Work Location And Conditions

• At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii Michigan and Tennessee.
• You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.
• You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.

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Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.