Senior Director/Vice President Clinical Pharmacology

Join Us in Tackling Autoimmune Disease at Its Root

At Vor, we believe science can do more than manage symptoms. It can change the course of disease. By advancing telitacicept, a first- and potentially best-in-class dual BAFF/APRIL inhibitor, we are silencing upstream survival signals and stopping downstream autoimmune cascades. Together, we are addressing disease at its root cause and rewriting what is possible for patients worldwide.

When you join Vor, you’re not just working on a medicine. You’re part of a mission to redefine the future of autoimmune care.

Why Work at Vor?

Impact: Contribute directly to a medicine with best-in-disease Phase 3 results in myasthenia gravis and expansion into multiple autoimmune diseases.

Growth: Be part of a rapidly scaling company with opportunities to grow your career in science, clinical development, commercial strategy, and beyond.

Innovation: Work on a platform with potential beyond one indication — a therapy that has already shown consistent results across lupus, IgA nephropathy, and Sjögren’s syndrome.

Belonging: Join a culture where every voice is heard, and where our shared mission unites us across functions and geographies.

The Senior Director/Vice President Clinical Pharmacology will build the clinical pharmacology function to enable the design and efficient execution of all Phase 2-3 programs across multiple autoimmune therapeutic areas. Responsibilities will include providing strategic drug development input, provide clinical pharmacology expertise to cross–functional teams and facilitate the execution of on-going and future programs at Vor. In addition, the role will require the development of strong working relationships within Clinical Development Department and with other key functions including, for example, Pharmacovigilance and Drug Safety, Regulatory, Discovery, CMC, Translational, Trial Operations, Biostatistics and Program Management.

Key Responsibilities:

• Build the clinical pharmacology department to support Vor’s pipeline
• Provide strategic and clinical pharmacology leadership to all development programs
• Develop stage-gated and flexible financial and human resource approach to account for evolving requirements for each program
• Develop and implement new clinical pharmacology tools and technologies to drive smarter drug development for programs, where appropriate
• Represent the clinical pharmacology department function and provide subject matter expertise to cross-functional project teams
• Develop and maintain collaborative working relationships with colleagues within and outside the department
• Author/review/approve clinical protocols, analysis plans, study reports and regulatory submissions
• Develop high quality clinical pharmacology plans and content for global regulatory submissions, including INDs, protocols and IBs etc.
• Develop and propose short- and long-term objectives for early clinical development in accordance with overall Company strategies and goals
• Plan and manage budget proposals and approved budgets in accordance with Vor’s strategic and operating plans and Finance policies
• Build out the Clinical pharmacology department as the number of programs increase which includes recruiting, leading, directing, and developing direct reports, in accordance with the Company’s Human Resource policies and practices
• Act in accordance with Company policies, including, for example, the Code of Business Conduct and Ethics and ensure policies are understood and followed by direct reports, if any
• Some international travel may be required
• Other duties as assigned

Qualifications:

• Ph.D. or MD with a minimum of 12+ years of experience in clinical pharmacology roles of increasing leadership and scope in the autoimmune area
• Prior successful experiences in supporting global regulatory interactions, including INDs, EOP1/2, and scientific advice
• Proven experience in leading and managing sophisticated scientific teams
• Excellent communication skills and ability to effectively collaborate with cross-functional teams and influence decision making process
•  Hands on experience in design and executing a variety studies
• Appropriate publication records in top-tier and peer-reviewed journals are required to establish credibility with a highly talented scientific team
• Some US and international travel required

At Vor, we support our team with robust benefits, including comprehensive health coverage, flexible paid time off, generous parental leave, and a competitive 401(k). From education assistance to wellness resources and financial security, we invest in your well-being so you can thrive at work and beyond.

As an equal opportunity employer, we at Vor Bio know that diversity inspires innovation, inclusiveness, and creativity. We invite you to come as you are. All applicants will be considered for employment agnostic to race, age, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

Please visit our website at https://www.vorbio.com/ for more information.