Sr. Director - Operational Excellence and Transformation

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Organization Overview:

At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.

The Bioproduct Research and Development (BR&D) organization strives to deliver innovative medicines to patients through the development and commercialization of monoclonal antibodies, novel therapeutic proteins, peptides, bioconjugates, cell therapies, gene therapies, and other genetic medicines etc. This organization is a multidisciplinary group that works collaboratively with our discovery, manufacturing and quality, business units.

The Senior Director, Operational Excellence and Transformation, is responsible for evaluating the existing operational framework and workflows, and then developing data-driven strategies to improve efficiency across the biologics drug substance organization spanning both development and clinical manufacturing functions. This role collaborates closely with function heads to establish a strong foundation and foster a sustainable culture of innovation and continuous improvement that drives measurable productivity gains.

Key Responsibilities

1. Collaborate with functional SMEs to document detailed workflows and create structured business process maps that provide a clear understanding of current operations.
2. Develop a robust and effective system to capture relevant data that supports informed, data-driven decision-making (e.g. resource allocation and business planning).
3. Establish high-level strategy aligned to departmental objectives, with a clear roadmap of transformation initiatives tailored for each function.
4. Collaborate with function heads to Identify, prioritize, and execute projects for productivity improvement. Develop and monitor KPIs as well as applicable tracking models to quantify benefits.
5. Design and implement standardized methods, tools, and templates for problem solving, daily management, and etc.
6. Deliver systematic training in useful Lean/Sigma methodologies to the team.  
7. Promote a culture of continuous improvement, encourage smart and efficient ways of working, and drive creative solutions within existing constraints.
8. Bachelor’s degree in engineering, life sciences, manufacturing, or related discipline; advanced degree preferred.
9. 10+ years of experience in industrial operations, business process improvement, or continuous improvement, with a proven track record of driving operational excellence.
10. Understanding of pharmaceutical R&D operations, with emphasis on CMC and GMP manufacturing, is a plus.

Basic Qualifications

Additional Skills And Preferences:

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$151,500 - $244,200

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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