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Software Engineer, Data Integration

Chan Zuckerberg Biohub.com

Office

Redwood City, CA (Onsite)

Full Time

The Team

To develop a dynamic, integrated view of biological systems in health and disease, the Chan Zuckerberg Institute for Advanced Biological Imaging (CZ Imaging Institute) aims to push forward the development and application of new imaging technologies over the next 10 to 15 years. CZ Imaging Institute researchers will collaboratively develop breakthrough biological imaging systems centered around grand challenges that push the boundaries of what we can see and measure to obtain deep insights into the architecture of complex biological systems at the molecular level.

As an extension of the Chan Zuckerberg Initiative’s Imaging program, the CZ Imaging Institute (https://czii.org/) will create breakthrough technologies — hardware, software, biological probes, data, and platforms — that will be made available to the scientific community and adopted worldwide through a combination of direct access to the Institute, open sharing of advances, and commercial partnerships.

The Opportunity

To accomplish our mission, we need to develop a dynamic, integrated view of biological systems in health and disease. As an extension of the Chan Zuckerberg Initiative’s Imaging Program, the CZ Imaging Institute aims to push forward the development and application of new imaging technologies over the next 15 years to obtain deep insights into the architecture of complex biological systems at the molecular level. 

The CZ Imaging Institute will create breakthrough technologies — hardware, software, biological probes, data, and platforms — that will be made available to the scientific community and adopted worldwide through a combination of direct access to the institute, open sharing of advances, and commercial partnerships. Researchers will collaboratively develop breakthrough biological imaging systems centered around grand challenges that push the boundaries of what we can see and measure.

The Chan Zuckerberg Imaging Institute is seeking an experienced Software Engineer, Data Integration, to work under a technology team leader and collaborate in developing software that supports automation of the workflow for high-end microscopic instruments. Will work closely with researchers, scientists, and engineers developing novel approaches in cryoEM.

What You'Ll Do

  • Perform core development of in-house software that tracks sample preparation, data acquisition, visualization, and analysis workflow across multiple imaging modalities.
  • Develop a user interface to the workflow.
  • Develop curation tools for the deposition of such data into the CryoET Data Portal for community use.
  • Identify and implement steps of the workflow suitable for AI integration.
  • Interact with software and data engineers from other CZ Science efforts in integrating data from different modalities.

What You'Ll Bring

Essential -

  • BS or MS in Computer Science or a comparable/relevant degree.
  • 1-5 years of professional software development experience.
  • Strong background in database design and architecture.
  • Proficient in Python and JavaScript, with hands-on experience in front-end frameworks such as React and Next.js
  • Familiarity with requirements for integrating web-based viewers for large scientific or medical images.
  • Well developed analytical observation and software optimization skills.
  • Deep understanding of software engineering principles and design patterns and how to apply them.
  • Excellent problem solving skills.
  • Excellent communication skills.

Nice to have -

  • Development and optimization in high-performance computing (HPC) environments.
  • Knowledge of image formats and streaming methods (e.g., TIFF, Zarr pyramids) for efficient web delivery.
  • Experience collaborating cross-functionally with scientists.
  • An interest in science and learning about biological imaging.
  • Experience in open source project.
  • Diverse experience working with both desktop and web applications and understanding how they can interface with each other.

Compensation

The Redwood City, CA base pay range for a new hire in this role is 153,000.00 - 191,000.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. 

Benefits For The Whole You

We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible. 

  • Provides a generous employer match on employee 401(k) contributions to support planning for the future.
  • Paid time off to volunteer at an organization of your choice.
  • Funding for select family-forming benefits.
  • Relocation support for employees who need assistance moving

If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.

#Li-Onsite

Software Engineer, Data Integration

Office

Redwood City, CA (Onsite)

Full Time

October 1, 2025

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Chan Zuckerberg Biohub

czbiohub