Precision Medicine Medical Affairs Global Strategic Lead

General Information

Job Advert Title Precision Medicine Medical Affairs Global Strategic Lead Location United Kingdom Function/Business Area Medical & Clinical Employment Class Permanent

Description

Precision Medicine MA Global Strategic Lead
About Astellas
At Astellas we are a progressive health partner, delivering value and outcomes where needed.
We pursue innovative science, focusing initially on the areas of greatest potential and then developing solutions where patient need is high, often in rare or under-served disease areas and in life-threatening or life-limiting diseases and conditions.
We work directly with patients, doctors and health care professionals on the front line to ensure patient and clinical needs are guiding our development activities at every stage.
Our global vision for Patient Centricity is to support the development of innovative health solutions through a deep understanding of the patient experience. At Astellas, Patient Centricity isn’t a buzzword - it’s a guiding principle for action. We believe all staff have a role to play in creating a patient-centric culture and integrating an awareness of the patient into our everyday working practices, regardless of our role, team or division.
We work closely with regulatory authorities and payers to find new ways to ensure access to new therapies. We deliver the latest insights and real-world evidence to inform the best decisions for patients and their care-givers, to ensure the medicines we develop continue to provide meaningful outcomes.
Beyond medicines, we support our stakeholder communities to drive initiatives that improve awareness, education, access and ultimately standards of care.
Opportunity:
The Medical Affairs Global Strategic Brand Lead (MA GSBL) for Precision Medicine (PM) provides strategic direction for CDx/Biomarkers throughout late development, launch, and post-launch phases. The role ensures CDx strategies are embedded in the Core Medical Plan (CMP) and leads on evidence generation and dissemination. Key responsibilities include overseeing CDx/PM tactics, aligning with the Commercial PM team to drive business growth, collaborating with co-creation countries to advance diagnostic and medical objectives, and capturing external insights to inform the global PM strategy.
Hybrid Working:
At Astellas we recognise the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimise the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines.
Responsibilities and Accountabilities:
Strategic Leadership:

• Leading the development of the Medical Product Strategy (MPS) and ensuring CDx strategies and tactics are embedded in the Core Medical Plan (CMP)
• Contributing to the creation of the Integrated Evidence Generation Plan (iEGP) with cross-functional experts, establishing the strategic foundation for evidence generation
• Defining and overseeing overarching objectives with medical KPIs, ensuring alignment across global and local strategies

Medical Affairs Excellence:

• Leading a high-impact team accountable for delivering CDx/PM evidence generation and dissemination tactics in the CMP, ensuring seamless execution that balances global objectives with local needs
• Managing budgets for global evidence generation and dissemination activities
• Empowering and enabling affiliates to deliver CDx/PM non-evidence generation and dissemination tactics, fostering dialogue to address local needs
• Ensuring robust governance and review of all CDx/PM MA study synopses and protocols, maintaining high standards for evidence generation
• Implementing the Integrated Evidence Dissemination Plan with strong scientific messages, providing centralized resources and iterative feedback to refine messaging
• Enabling execution of CDx/PM tactics in the global launch plan, defining KPIs and metrics to track progress
• Supporting internal and external medical education on CDx/Biomarkers in new disease areas and innovative treatment modalities

Cross-Functional Collaboration:

• Fostering collaboration across Commercial, Market Access, Development, Patient Centricity, and Medical Affairs (local, regional, co-creation) to align strategies and implement CDx/PM tactics addressing patient and HCP needs
• Partnering with R&D to shape CDx/Biomarker development, ensuring clinical viability and patient access at launch
• Communicating insights from advisory interactions and Field Medical to drive timely responses to evolving needs
• Driving cross-geography alignment for consistent medical affairs execution and CDx/PM messaging

Stakeholder Engagement:

• Building and maintaining relationships with diagnostic partners, testing labs, external experts, advocacy groups, medical organizations, and regulatory bodies to strengthen the company’s global presence in Precision Medicine
• Acting as a trusted representative in external forums, conferences, and industry partnerships
• Coaching and Team Development:
• Coaching and developing team members while driving cultural and operational transformation initiatives, fostering behaviours aligned with the Astellas Way and CMT Ways of Working, and preparing the organization for long-term sustainable success

Compliance and Ethics:

• Embedding a strong compliance culture across all activities and acting as a role model for ethical behaviour, fostering integrity and accountability throughout the organization.

Required Experience:

• Extensive experience in progressive leadership experience in Pharmaceutical Medicine, including solid experience in the CDx/PM space, ideally within Medical Affairs, pharmaceutical/diagnostic companies, commercial laboratories, or academic institutions
• Leading cross-functional, geographically diverse matrix teams and influencing without direct authority to deliver high-impact business results
• Driving brand medical affairs strategy, including product launches and lifecycle management
• Developing innovative, patient-centered evidence generation and dissemination strategies to support patient access and brand performance
• Strong understanding of industry trends, regulatory environments, and market access pathways for CDx
• Advanced knowledge of global pharma regulations and guidelines (IFPMA, PhRMA, FDA, EMA, PMDA, ACCME, OIG) with the ability to apply legal and compliance considerations to Medical Affairs activities
• Managing large budgets with proactive risk management for timelines and financial performance

Skills and Leadership:

• Leading and inspiring high-performing global matrix teams while applying strategic thinking, business acumen, and strong communication and influencing skills to drive results in complex, fast-paced environments

Education:

• A medical degree (MD or equivalent) or Doctorate degree in Pharmacy or Pharmacology recognized by one of the leading governing bodies from around the globe or equivalent. 
• Medically qualified with at solid experience in direct patient care 
• Work experience across multiple cultures and countries / regions.

Working Environment:

• The is a permanent full-time position based in the UK.
• This position follows our hybrid working model. Role requires a blend of home and minimum of 1 day a quarter in our Addlestone office. Flexibility may be required in line with business need. Candidates must be located within a commutable distance of the office.

We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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