Spring 2026 Co-op: Immunobiology Assay Development

Company Overview:

Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.  

Prime Medicine is currently progressing a diversified portfolio of investigational therapeutic programs organized around our core areas of focus: hematology, immunology & oncology, liver and lung. Across each core area, Prime Medicine is focused initially on a set of high value programs, each targeting a disease with well-understood biology and a clearly defined clinical development and regulatory path, and each expected to provide the foundation for expansion into additional opportunities. For more information, please visit www.primemedicine.com.

Co-Op Assignment Overview

Prime Medicine is seeking a co-op for the Spring 2026 cycle with knowledge in cell and molecular biology to join the Immunobiology team. The qualified candidate will work hands-on with a highly collaborative, fast-paced project team to support Prime Editor selection by understanding the associated immunobiology. In this position, you will learn cell and molecular biology skills and develop a deep understanding of gene editing and immunology.

Primary Responsibilities:

• Processing tissues into single cell suspensions for use immunobiology assays
• Aseptic culture of primary and immortalized mouse and human cells
• Setting up, performing, and collecting and analyzing data for in vivo, ex vivo, and in vitro immunogenicity assays
• Preparing cell samples for flow cytometry assays
• Data analysis, interpretation, and presentations within the team

Qualifications:

• B.S. candidate in Cell & Molecular Biology or related discipline
• Basic knowledge of molecular biology, cell biology and biochemistry
• Excellent troubleshooting and communication skills
• Ability to work independently and within a team

Preferred Qualifications:

• Hands-on experience with aseptic cell culture of mammalian cells
• Experience with tissue dissociation
• Experience with flow cytometry
• Familiarity with Excel and PowerPoint for data analysis
• Independently motivated, detail-oriented, and excellent problem-solving abilities

What We Offer:

• A cutting-edge team open to mentorship and networking.
• Full reimbursement for monthly commuting costs including MBTA, Commuter Rail, or Bluebikes, etc.
• Participation in regular seminars with industry experts.
• Full participation in employee activities including learning and development offerings, social activities, etc.

NOTE: We are currently not considering co-op candidates outside of the local Boston/Cambridge area.

Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.