Enterprise Application Solutions Architect

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.

Summary

The Enterprise Application Solutions Architect will serve as the strategic lead for enterprise application administration, with a focus on the design, implementation, and lifecycle management of major COTS/SaaS initiatives. This role is responsible for architecting scalable, secure, and integrated solutions that align with business objectives and technology standards. The architect will guide cross-functional teams through complex deployments, ensure robust vendor partnerships, and drive innovation across the enterprise application ecosystem.

This role requires deep technical expertise, strong project management capabilities, and the ability to translate business needs into actionable technology strategies. The Solutions Architect will mentor administrators, establish architectural best practices, and ensure that enterprise applications deliver measurable value across the organization.

Job Responsibilities

• Lead the design and implementation of enterprise COTS/SaaS solutions through its full lifecycle, ensuring scalability, security, and alignment with business goals.
• Serve as the technical authority and escalation point for enterprise application administrators.
• Architect and oversee integrations using IPaaS platforms (e.g., Celigo, Workato, Boomi), ensuring maintainability and performance.
• Collaborate with stakeholders to evaluate new technologies, define solution roadmaps, and prioritize initiatives.
• Develop and enforce architectural standards, governance models, and documentation practices.
• Guide vendor selection, contract negotiation, and licensing strategy to ensure cost-effective and compliant application management.
• Oversee the creation of SOPs, knowledgebase articles, and support documentation to enable efficient operations and user adoption.
• Monitor application performance, usage metrics, and support trends to inform continuous improvement.
• Lead cross-functional workshops and technical reviews to align solutions with enterprise architecture and compliance requirements.

People Manager

• No

 Education, Experience, and Skills

• Proven ability to architect and implement enterprise-grade SaaS solutions.
• Strong understanding of integration patterns, automation, and API management.
• Experience in regulated environments (HIPAA, HITRUST) and familiarity with compliance frameworks.
• Excellent communication skills with the ability to translate technical concepts for non-technical audiences.
• Proficiency in scripting, automation, and enterprise productivity tools (e.g., Jira, Confluence, Smartsheet).
• Experience with AI-enhanced productivity platforms (e.g., M365 Copilot) is a plus.
• 5+ years of experience in enterprise application architecture or solution design.
• 3+ years of experience leading COTS/SaaS implementations and integrations.
• 3+ years of vendor management and contract negotiation.
• Experience with project management and service management platforms (e.g., Jira, ServiceNow).
• Demonstrated success in mentoring technical teams and driving enterprise-wide initiatives.
• Experience leading cross-functional teams or enterprise-wide transformation initiatives.

Certificates, Licenses, Registrations

• Relevant certifications in enterprise architecture, SaaS platforms, or integration tools preferred

Physical Demands

• Ability to stand, walk, and sit for extended periods.

Work Environment

• Work is primarily performed in a remote office setting.

#Li-Remote

Pay Transparency, Budgeted Range$153,053—$191,317 USD

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Science - Minded, Patient - Focused. 

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most. 

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.

SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.

From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:

Technical Expertise

• High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
• Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.

Clinical Expertise

• Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
• Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
• Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.

Learn more About Us here.

Our Culture

At GeneDx, we are dedicated to cultivating an environment where creativity and innovation thrive. We believe in the power of community and collaboration, where diverse perspectives are embraced, and every voice contributes to our shared success. Our team is a vibrant mix of professionals who challenge and support each other in equal measure, fostering growth both personally and professionally. When you join us, you're not just taking on a job—you're joining a movement. A movement that champions curiosity, embraces change, and believes in making an impact, one patient at a time. Cultural principles we live by:  

• Be bold in our vision & brave in our execution. 
• Communicate directly, with empathy. 
• Do what we say we're going to do.  
• Be adaptable to change.  
• Operate with a bias for action.    

Benefits Include:

• Paid Time Off (PTO)
• Health, Dental, Vision and Life insurance
• 401k Retirement Savings Plan
• Employee Discounts
• Voluntary benefits
• GeneDx is an Equal Opportunity Employer.
• All privacy policy information can be found here.