Principal Statistical Programmer

Join Clario’s industry-leading Digital Physiology team as a Principal Statistical Programmer, where your expertise will drive innovation in clinical research. This is a unique opportunity to lead advanced statistical programming for cardiac safety trials, shaping the future of digital health through cutting-edge data science and global collaboration.

What We Offer

• Competitive compensation + shift allowances
• Attractive benefits (security, flexibility, support and well-being)

• Engaging Employee Programs

• Technology for hybrid working and great onsite facilities

What you'll be doing

Statistical Programming & Data Standards

• Lead and coordinate all statistical programming activities for cardiac safety trials.
• Develop, test, and maintain SAS code to generate CDISC-compliant datasets (SDTM, ADaM).
• Produce and maintain submission-ready datasets and electronic submission packages (e.g., define.xml, reviewer’s guide) in accordance with FDA guidelines.

Team Leadership & Mentorship

• Manage direct reports in a line or matrix capacity, including work allocation, resource planning, and professional development.
• Conduct onboarding and training on statistical programming practices and SOPs.
• Mentor junior staff and provide guidance on programming methodologies and quality standards.

Process Improvement & Strategic Initiatives

• Identify and implement process improvements to enhance operational efficiency.
• Develop and maintain SOPs, SWIs, templates, and playbooks for programming deliverables.
• Drive initiatives for future analyses, data quality, and standardization.

Cross-functional Collaboration & Project Management

• Collaborate with cross-functional teams to define scope and timelines for statistical deliverables.
• Manage client commitments and ensure timely delivery of assigned projects.
• Maintain accurate tracking of deliverable statuses and dates.
• What we're looking for
• Ph.D. with 5+ years of relevant industry experience, M.S. with 7+ years of relevant industry experience or B.S. with 10+ years of relevant industry experience
• A degree in medical, health, public, or general science—or an equivalent combination of education and experience sufficient to perform job duties
• Strong experience in clinical trials, preferably within a CRO or pharmaceutical research organization
• Proficiency in SAS programming, including creation, testing, and maintenance of CDISC-compliant datasets (SDTM, ADaM)
• Experience with electronic submission packages and regulatory interactions (e.g., FDA)
• Familiarity with clinical protocols and Statistical Analysis Plans
• Experience with TFL generation is a plus
• Solid understanding of the pharmaceutical drug development process

At Clario, our purpose is to transform lives by unlocking better evidence. It’s a cause that unites and inspires us. It’s why we come to work—and how we empower our people to make a positive impact every day. Whether you're advancing clinical science, building innovative technology, or supporting our global teams, your work helps bring life-changing therapies to patients faster.