Scientist II, Disease Mechanism Research

General Information

• Job Advert Title: Scientist II, Disease Mechanism Research
• Location: Tsukuba, Ibaraki
• Division: Oncology Research
• Employment Class: Permanent

Description

【募集の背景 / Purpose & Scope】

This is a biologist position developing anti-cancer drugs, including antibody-drug conjugates (ADCs), multi-specific antibodies or engineered small molecules in collaboration with discovery and program teams. Pathological Model and Analysis in Disease Mechanism Research group is at the forefront of Astellas Oncology Research validating novel therapeutic concepts and modalities leveraging cutting-edge science and assay technologies. The team is employing advanced assay systems that recapitulate pathophysiological conditions to fill the gaps in our understanding of MoA and efficacy of our pipeline utilizing platforms developed in-house and in collaboration with external partners. We are seeking a highly motivated and talented biologist to join our mission and help drive our dynamic research forward.

【職務の内容 / Essential Job Responsibilities】

（雇入れ直後）

・ Responsible for design, execution, and analysis of non-clinical biological studies necessary to validate novel therapeutic concepts and modalities of anti-cancer drugs leveraging cutting-edge science and assay technologies independently.

・ Leadership from the bench. This position is expected to demonstrate leadership through not only planning, and communication, but through hands-on execution of experiments and training of others.

・ Serves as a subject matter expert for cancer biology by remaining at the forefront of scientific advancement in clinical cancer pathophysiology and assay development (literature, scientific conference, etc.).

・ Prepares technical reports, summaries, protocols/SOPs, and presentations in English. Regularly presents findings in English at group meetings and to upper management to support program-level, data-driven decisions.

・ Supports cross-functional knowledge sharing and collaborate on research projects.

・ Collaborates across teams within Disease Mechanism Research group, and other teams within Oncology Research to advance development of Astellas programs and assets

・ May directly manage of one or more research associates to support assay development and analysis

・ Performs other duties as assigned or special projects as needed

（変更の範囲）

会社内での全ての業務

【就業環境に関する要件 / Specific Physical or Environmental Requirements】

This position is based in Tsukuba Research Center and will require on-site work.

【応募要件 / Qualifications】

＜必須 / Required＞

・ PhD with 5+ years or MS with 8+ years of relevant experience in cancer biology research

・ Deep expertise in cancer biology

・ Experience with biological (molecular/cellular) assessment of malignant cells as well as non-malignant cells including immune cells.

・ Demonstrated ability to lead from the bench

・ Successful management of scientific staff

・ Strong scientific communication skills in written and spoken English

・ Demonstrated success in leading projects and teams.

・ Capable to drive scientific innovation.

・ Demonstrated ability to critically analyse, interpret, and present scientific results

・ Strong organizational, time management, and problem-solving skills with scientific attention to detail

・ Work independently and ability to effectively collaborate with other teams

・ Excellent communication and interpersonal skills

・ Excellent work planning, organization and record keeping

・ Strong work ethic with a passion for working in a fast-paced, dynamic and diverse work environment

＜歓迎 / Preferred＞

・ Experience with microphysiological system (MPS) development

・ Prior industry experience

・ Background in immunology

・ Experience managing direct reports

【応募書類 / Application Documents】

和文履歴書（必須）・和文職務経歴書（必須）・英文レジュメ（任意）

Resumes

【選考プロセス / Selection details】

書類選考 → 1次面接 → 適性検査 → 最終面接

※変更の可能性もございますので、予めご了承下さい。

CV screening → First interview → Aptitude test → Final interview

*Please be advised that there might be a change in the process.

【勤務地 / Location】

（雇入れ直後）

茨城県つくば市　アステラス製薬　つくば研究センター

Tsukuba, Ibaraki

※ＪＲひたち野うしく駅とつくばエクスプレス（Tx)　研究学園駅より通勤バスがございます。

（変更の範囲）

会社の定める事業場および自宅

【勤務開始日 / Start Date】

応相談

Will be decided according to the candidate's flexibility

【契約期間 / Contract Duration】

期間の定めなし

Not limited to specified period

【試用期間 / Probation Period】

試用期間原則なし

No probation period in principle

【給与 / Salary】

①基本給：当人の経歴・技術・技能等を考慮して決定

②裁量労働制の場合：裁量労働手当として職務グレードに応じて50,000～100,000円支給

③フレックスタイム制の場合：月間の所定労働時間を超えて勤務する時間に対して時間外勤務手当を支給

①Base salary: will be decided by the candidate's experience, skill and capability.

②When Discretionary Work System is applied: Discretionary work allowance will be paid.(50,000～100,000yen, based on the Grade)

③When Flextime System is applied: Overtime allowance will be paid for time worked in excess of prescribed working hours.

【昇給 / Salary Raise】

有り

【賞与 / Bonus】

有り

【諸手当 / Allowance】

裁量労働手当、住宅手当、通勤手当　等

Discretionary work allowance, Housing allowance, Commutation allowance, etc.

【勤務時間 / Working Hours】

8:30～17:30（月～木）、8:30～15:45（金）、専門業務型 裁量労働制

裁量労働制の場合、所定労働時間を働いたものとみなす。

8:30～17:30（Mon～Thu）、8:30～15:45（Fri）

Discretionary Work System

【休日 / Holidays】

完全週休２日制（土曜・日曜）、祝日、5月1日、夏季、年末年始

Weekends(Sat and Sun), holidays, May 1st, summer vacation, New Year holidays

【休暇 / Vacation Leave】

年次有給休暇、育児休業制度、介護休業制度　等

Annual paid leave, childcare leave system, nursing care leave system, etc.

【福利厚生 / Welfare】

雇用保険、労災保険、厚生年金、健康保険、共済会制度、社宅制度、持株会制度、財形貯蓄制度　等

Employment Insurance, Industrial Accident Compensation Insurance, Welfare Pension Insurance, Health Insurance, Mutual Aid Association System, Company Housing System, Employee Shareholder Association System, Property Accumulation Savings System

• 【アステラス製薬　採用サイト/ Career web site】
• https://re-jp.astellas.com/jp/recruit/newgraduates/
• For more information about Astellas, please visit our career web site.

"We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law."