Scientific Program Manager, Platform Technology

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.

Summary 

The Scientific Program Manager, Platform Technologies will serve as the leading administrator for research projects between the Platform Technologies’ Team and internal and external interest holders.  This individual will work cross-functionally to coordinate research efforts that align with company objectives and to ensure that projects move forward.  Projects cover topics related to the quality and impact of our internal variant classification, the use of machine learning-based approaches in a clinical diagnostic setting, and the impact of next generation sequencing technologies in the diagnosis of rare disease cases.  The Scientific Program Manager will provide support to various internal and external collaborative research projects, including communicating with project interest holders, and working with the Internal Review Board and with our legal team to ensure compliance.  The Scientific Program Manager, Platform Technologies role requires a deep understanding of genetic testing methodologies, interpretation of sequence and structural variation, and the current trends in diagnostic genetic testing. 

Job Responsibilities

• Administers Platform Technology research portfolio ensuring that projects meet Medical Affairs objectives and progress in a timely fashion 
• Serves as point of contact for incoming research proposals supporting the completion of research proposals and the presentation of potential new collaborations at internal research meetings  
• Communicates with external and internal collaborators, and other interest holders in a timely fashion 
• Facilitates Research Agreement drafting and execution  
• Supports maintenance of IRB protocols and participant tracking    
• Maintains research documentation and databases  
• Consults (as needed) mutation databases and genome browsers 
• Ensures the accuracy, integrity, and security of clinical research data by implementing best practices in data management and quality control  
• Generates detailed reports and visualizations to communicate findings in a clear and concise manner to collaborative teams 
• Produces, tracks, and presents outputs from research protocols in collaboration with the team, including conference abstracts, posters, presentations, and manuscripts 
• Assists in the preparation or clinical review of materials for internal messaging or in support of efforts by the commercial and marketing teams  
• Performs other duties assigned in support of the team, department, or company objectives 

Education, Experience, and Skills

• Master’s degree in genetic counseling and board certification by the American Board of Genetic Counseling, required  
• 5+ years of experience in an industry role as a board-certified genetic counselor 
• 2+ years of experience working with software engineers and bioinformaticians  
• 2+ years of experience driving project management initiatives from gathering requirements for projects to overseeing their implementation and execution within specified timelines 
• Experience translating needs between technical and clinical teams, serving as a liaison between these teams to ensure successful execution of projects 
• Skilled at bridging cross functional teams (across technical and clinical domains) by facilitating communication among project collaborators  
• Excellent communication skills, with the ability to present complex data to diverse audiences 
• Ability to work effectively in a collaborative, team-oriented environment 
• High level of attention to detail  
• Familiar with ACMG guidelines for variant classification  
• Comfortable with human mutation databases, genome browsers, HGVS nomenclature, and Human Phenotype Ontology (HPO) 

Preferred:  

• Strong level of clinical genetics knowledge  
• Proficiency in working with databases  
• Proficiency in working with the Microsoft suite of products 

Certificates, Licenses, Registrations

• Certification by the American Board of Genetic Counseling (ABGC)

Physical Demands

• Ability to stand, walk, and sit for extended periods.

Work Environment

• Work is primarily performed in a remote office setting.
• The role may require occasional travel to attend relevant scientific conferences.
• Standard work hours are Monday through Friday, 9 AM to 5 PM EST.

#LI-REMOTE

Pay Transparency, Budgeted Range$153,053—$191,317 USD

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Science - Minded, Patient - Focused. 

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most. 

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.

SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.

From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:

TECHNICAL EXPERTISE

• High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
• Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.

CLINICAL EXPERTISE

• Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
• Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
• Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.

Learn more About Us here.

Our Culture

At GeneDx, we are dedicated to cultivating an environment where creativity and innovation thrive. We believe in the power of community and collaboration, where diverse perspectives are embraced, and every voice contributes to our shared success. Our team is a vibrant mix of professionals who challenge and support each other in equal measure, fostering growth both personally and professionally. When you join us, you're not just taking on a job—you're joining a movement. A movement that champions curiosity, embraces change, and believes in making an impact, one patient at a time. Cultural principles we live by:  

• Be bold in our vision & brave in our execution. 
• Communicate directly, with empathy. 
• Do what we say we're going to do.  
• Be adaptable to change.  
• Operate with a bias for action.    

Benefits include:

• Paid Time Off (PTO)
• Health, Dental, Vision and Life insurance
• 401k Retirement Savings Plan
• Employee Discounts
• Voluntary benefits

GeneDx is an Equal Opportunity Employer.

All privacy policy information can be found here.