RA/SRA BioAnalysis (CONTRACT)

Orna Therapeutics is an innovative biotechnology startup based in Watertown, MA, committed to developing groundbreaking therapies for diseases that current approaches cannot address. With our pioneering circular RNA technology, developed at MIT, we are at the forefront of advancing the next generation of RNA therapeutics. Our state-of-the-art expression and delivery platform positions us to tackle complex diseases, including B cell-driven autoimmune disorders, B cell malignancies, sickle cell disease, and beyond.

We are looking for a motivated RA/SRA to join the BioAnalysis team and support the nonclinical studies for the company’s diverse programs. The individual will actively participate in developing ligand binding assays (LBA) under supervision of scientists, perform sample testing and present results in team meetings. In this role you would have the opportunity to work with vibrant multi-disciplinary teams.

Responsibilities

• Tissue processing from mice, rat and NHP in-vivo studies for RNA and protein extraction.
• Independently execute LBA and qPCR to measure large molecules such as protein and RNA from plasma and tissues samples.
• Perform method development and trouble shooting on LBA and qPCR-based assay with guidance.
• Provide high quality bioanalytical support with a focus on quantifications for PK, TK, PD assessment.
• Deliver and present experimental results to the Pre-Clinical team.
• Maintain detailed experimental protocols, electronic laboratory notebook.

Qualifications

• Major in biology, chemistry, pharmaceutical science or related fields.
• Bachelor with 0-4 years of related industry or academic experience, or MS with 0-2 years of related industry or academic experience.
• Experience in and knowledge of RT-QPCR, bDNA and ligand binding assay.
• Ability to perform data analysis using excel and GraphPad prism.
• Highly motivated, team-oriented, and excellent communication skills.
• Experience with Ligand binding assays on Luminex and MSD platform is a plus.
• Experience in tissue sample processing is a plus.
• Willingness to learn new techniques.
• Ability to communicate effectively in a group setting.

Why Orna? At Orna Therapeutics, we’re more than just a workplace—we’re a community. We believe in fostering an environment where individuals can grow, thrive, and make a lasting impact on the future of healthcare. Join us as we revolutionize RNA therapeutics and make a difference in the lives of patients around the world.

Equal Employment Opportunity Statement

Individuals seeking employment at Orna Therapeutics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation. 

We are unable to sponsor visas for contract roles.